Maksym Shyian



2006–2010 BSc in Biology National University of Kyiv, Ukraine
2010–2012 MSc in Biochemistry and Molecular Biology National University of Kyiv, Ukraine
2012-2018 PhD in Biology University of Geneva, Switzerland (supervisor: David Shore)
2018-2019 Postdoctoral Research Fellow University of Geneva (supervisor: David Shore)
2020-present Postdoctoral Research Fellow Harvard Medical School (supervisor: Johannes Walter)
Awards and honors
2005 Silver Medal at the 16th International Biology Olympiad, Beijing, China
2006 Gold Medal at the 17th International Biology Olympiad, Rio Cuarto, Argentina
2010–2012 National Scholarship Program “Zavtra.UA” for 2010/11 and 2011/12, Ukraine
2015 Epstein Award, Dpt. MolBiol, University of Geneva, Switzeland
2020–2021 Swiss National Science Foundation ‘Early Postdoc.Mobility’ Fellowship

Shyian M, Albert B, Zupan AM, Ivanitsa V, Charbonnet G, Dilg D, Shore D. Fork Pausing Complex Engages Topoisomerases at the Replisome. Gen Dev. 2020. 34(1-2):87-98. doi: 10.1101/gad.331868.119. Epub 2019 Dec 5

Hafner L, Lezaja A, Zhang X, Lemmens L, Shyian M, Albert B, Follonier C, Nunes JM, Lopes M, Shore D, Mattarocci S. Rif1 Binding and Control of Chromosome-Internal DNA Replication Origins Is Limited by Telomere Sequestration. Cell Rep. 2018. 23(4):983-992. doi: 10.1016/j.celrep.2018.03.113.

Mattarocci S, Reinert JK, Bunker RD, Fontana GA, Shi T, Klein D, Cavadini S, Faty M, Shyian M, Hafner L, Shore D, Thomä NH, Rass U. Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends. Nat Struct Mol Biol. 2017. 24(7):588-595. doi: 10.1038/nsmb.3420. Epub 2017 Jun 12.

Shyian M*, Mattarocci S*, Albert B, et al. (2016) Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication. PLoS Genet 12(11): e1006414. doi:10.1371/journal.pgen.1006414 (*co-first authors)

Mattarocci S, Hafner L, Lezaja A, Shyian M, Shore D. Rif1: A Conserved Regulator of DNA Replication and Repair Hijacked by Telomeres in Yeasts. Front Genet. 2016. doi: 10.3389/fgene.2016.00045. eCollection 2016.

Mattarocci S*, Shyian M*, Lemmens L, et al. Rif1 controls DNA replication timing in yeast through the PP1 phosphatase Glc7. Cell Rep. 2014. 7(1):62-9. (*co-first authors)

Kostianets O, Shyian M, Sergiy D, et al. Serological Analysis of SEREX-Defined Medullary Breast Carcinoma-Associated Antigens. Cancer Invest. 2012. 30(7):519-27.

Kiyamova R, Garifulin O, Gryshkova V, Kostianets O, Shyian M, Gout I, Filonenko V. Preliminary study of thyroid and colon cancers-associated antigens and their cognate autoantibodies as potential cancer biomarkers. Biomarkers. 2012. 17(4):362-71. doi: 10.3109/1354750X.2012.677476. Epub 2012 May 22.

Kiyamova R, Shyian M, Lyzogubov VV, Usenko VS, Gout T, Filonenko V. Immunohistochemical analysis of NaPi2b protein (MX35 antigen) expression and subcellular localization in human normal and cancer tissues. Exp Oncol. 2011. 33(3):157-61.

Shyian M, Gryshkova V, Kostianets O, et al. Quantitative analysis of SLC34A2 expression in different types of ovarian tumors. Exp Oncol. 2011. 33(2):94-8.



Reading science fiction, jogging, singing while working or doing dishes