Olga Kochenova

Post-doc

617-432-2927

Education
2003-2007 B.S. Biology Saint Petersburg State University, Russia
(supervisor: Elena I. Stepchenkova)
2007-2009 M.S. Biology (Genetics) Saint Petersburg State University, Russia
(supervisor: Elena I. Stepchenkova)
2010-2016 Ph.D. Oncology and Cancer Biology University of Nebraska Medical Center
(supervisor: Polina V. Shcherbakova)
2016-Present Postdoctoral fellow Harvard Medical School
(supervisor, Johannes Walter)
Awards and Honors
2013-2015 UNMC Program of Excellence Graduate Assistantship
Publications

Deng, L., Wu, R.A., Sonneville, R., Kochenova, O.V. , Labib, K., Pellman, D., Walter, J.C (2019). Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements. Mol Cell73(5): 915-929.

Wu, R.A., Semlow, D.R., Kamimae-Lanning, A.N., Kochenova, O.V. , Chistol, G., Hodskinson, M.R., Amunugama, R., Sparks, J.L., Wang, M., Deng, L., Mimoso, C.A., Low, E., Patel, K.J., Walter, J.C. (2019). TRAIP is a master regulator of DNA interstrand crosslink repair. Nature. doi:10.1038/s41586-019-1002-0.

Kochenova O.V.*, Bezalel-Buch R.*, Tran P., Chabes A., Burgers P.M.J. and Shcherbakova P.V. (2017). Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations. Nucleic Acid Res45(3): 1200-1218.
(* these authors contributed equally)

Kochenova O.V., Daee D.L., Mertz T.M., Shcherbakova P.V. (2015). DNA Polymerase ζ-Dependent Lesion Bypass in Saccharomyces cerevisiae Is Accompanied by Error-Prone Copying of Long Stretches of Adjacent DNA. PLoS Genet. 11(3): e1005110.

Stepchenkova E.I., Kochenova O.V., Zhuk A.S., Andreĭchuk Iu.V., Inge-Vechtomov S.G. (2011). Phenotypic expression and inter-conversion of primary lesions of genetic material detectable in the alpha-test in yeast Saccharomyces cerevisiaeGig Sanit.: 64-9.

Sharma N.M., Kochenova O.V., Shcherbakova P.V. (2011). The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell nuclear antigen (PCNA) regulates the Rev1-PCNA interaction and Polζ/Rev1-dependent translesion DNA synthesis. J Biol Chem. 286(38): 33557-66.

Kochenova O.V., Soshkina J.V., Stepchenkova E.I., Inge-Vechtomov S.G., Shcherbakova P.V. (2011). Participation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in yeast Saccharomyces cerevisiaeBiochemistry (Moscow). 76(1): 49-60.

Northam M.R., Robinson H.A., Kochenova O.V., Shcherbakova P.V. (2010). Participation of DNA polymerase ζ in replication of undamaged DNA in Saccharomyces cerevisiaeGenetics. 184(1): 27-42.

Hobbies
Argentine tango, painting, traveling