Investigating Mechanisms Of Genome Maintenance

Brandon Case

Brandon Case
Brandon_Case hms.harvard.edu
617-432-2927
 
Education
2009-2013 B.S. Chemistry Western New England University
2013-2019 PhD Molecular Biology & Biochemistry Wesleyan University (supervisor: Manju Hingorani)
2019-Present Postdoctoral fellow Harvard Medical School (supervisor: Johannes Walter and Joseph Loparo)
 
Publications
 
Case, B.C., Hartley, S., Osuga, M., Jeruzalmi, D., Hingorani, M.M. (2019). The ATPase mechanism of UvrA2 reveals the distinct roles of proximal and distal ATPase sites in nucleotide excision repair. Nucleic Acids Res. 47(8): 4136-4152.
 
LeBlanc, S.J., Gauer, J.W., Hao, P., Case, B.C., Hingorani, M.M., Weninger, K.R., Erie, D.A. (2018). Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS. Nucleic Acids Res. 46(20): 10782-10795.
 
De, S., Kaus, K., Sinclair, S., Case, B.C., Olson, R. (2018). Structural basis of mammalian glycan targeting by Vibrio cholerae cytolysin and biofilm proteins. PLoS Pathog. 14(2): e1006841.
 
Gauer, J.W., LeBlanc, S., Hao, P., Qiu, R., Case, B.C., Sakato, M., Hingorani, M.M., Erie, D.A., Weninger, K.R. (2016). Single-Molecule FRET to Measure Conformational Dynamics of DNA Mismatch Repair Proteins. Methods Enzymol. 581: 285-315.
 
Hobbies
 

Cooking, woodworking and astronomy