Geylani Can

Post-doc

617-432-2927

Education
2005-2009 B.S. Department of Molecular Biology and Genetics (Honours degree) Izmir Institute of Technology
2010-2012 Master Thesis Karolinska Institute (supervisor, Boris Zhivotosky)
2012-2018 Ph.D. in Molecular Biology University of Cambridge (supervisor, Philip Zegerman)
2019-Present Postdoctoral fellow Harvard Medical School (supervisor, Johannes Walter)
Awards and honors
2020-2024 AACR-Cancer Research UK Transatlantic Early Career Development Fellowship
2015 3rd place in Cambridge startup weekend, UK
2011 Best Poster Award in the 1st International Conference on Stem Cell Research and Applications, Turkey
2011 Sureyya Tahsin Aygun Best Poster Award in the Regenerative Medicine and Cellular Therapy Congress , Turkey
2009 Travel Grant from European Hematology Association, Germany
Publications
Johnson, M. C., Can, G., Santos, M. M., Alexander, D., and Zegerman, P. (2021). Checkpoint inhibition of origin firing prevents inappropriate replication outside of S-phase. Elife, 10, e63589.

Can, G., Kleinert, C., Macak, D. and Zegerman, P. (2019). Helicase subunit Cdc45 targets the checkpoint kinase Rad53 to both replication initiation and elongation complexes after fork stalling. Molecular Cell73:562-573.

Can, G., Akpinar, B., Baran, Y., et al. (2013). 5-Fluouracil signaling through a calcium-calmodulin dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells.Oncogene32(38):4529-38.

Sunay, O. Can, G., Çakır, Z., et al. (2013). Autologous rabbit adipose tissue derived mesenchymal stem cells for the treatment of bone injuries with distraction osteogenesis. Cytotherapy15(6): 690-702.

Can, G., Cakir, Z., Kartal, M., et al. (2012). Apoptotic effects of resveratrol, a grape polyphenol, on Imatinib-sensitive and resistant K562 chronic myeloid leukemia. cells.Anticancer Research32(7):2673-8.

Ekiz, H.A., Can, G., Baran, Y. (2012). Role of autophagy in the progression and suppression of leukemias. Crit Rev Oncol Hematol81(3): 275-85.

Can, G., Ekiz, H.A., Baran, Y. (2011). Imatinib induces autophagy through BECLIN-1 and ATG5 genes in chronic myeloid leukemia cells. Hematology16(2): 95-9.

Ekiz, H.A., Can, G., Gunduz, U., Baran, Y. (2010). Nilotinib significantly induces apoptosis In Imatinib resistant K562 cells, as effectively as in parental sensitive counterparts. Hematology15(1): 33-38.


Hobbies
Paragliding, hiking, climbing and camping