Ben Stinson

Post-doc (co-mentored with Joe Loparo)


2005-2009 B.A./M.S. Biochemistry University of Pennsylvania
2009-2015 Ph.D. Biochemistry Massachusetts Institute of Technology (supervisor: Bob Sauer)
2015-Present Postdoctoral Fellow Harvard Medical School (supervisor: Johannes Walter and Joseph Loparo)
Awards and honors
2013-2014 Poitras Predoctoral Fellowship, Massachusetts Institute of Technology
2016-Present Damon Runyon Postdoctoral Research Fellow

Stinson, B. M., Loparo, J. J. (2021). Repair of DNA Double-Strand Breaks by the Nonhomologous End Joining Pathway. Annual Review of Biochemistry, 90.

Saunders, R. A., Stinson, B. M., Baker, T. A., Sauer, R. T. (2020). Multistep substrate binding and engagement by the AAA+ ClpXP protease. PNAS. 117(45): 28005-28013.

Fei, X., Bell, T. A., Jenni, S., Stinson, B. M., Baker, T. A., Harrison, S. C., Sauer, R. T. (2020). Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife. 9: e52774.

Stinson, B.M., Moreno, A.T., Walter, J.C., Loparo, J.J. (2019). A Mechanism to Minimize Errors during Non-homologous End Joining. Mol. Cell. doi:10.1016/j.molcel.2019.11.018

Saunders, R. A., Stinson, B. M., Sauer, R. T. (2016). Assessing Substrate Engagement by Single Molecules of the AAA+ Protease ClpXP. The FASEB Journal. 30: 597-1.

Stinson, B.M., Baytshtok, V., Schmitz, K.R., Baker, T.A., Sauer, R.T. (2015). Subunit asymmetry and roles of conformational switching in the hexameric AAA+ ring of ClpX. Nat. Struct. Mol. Biol. 22: 411-416.

Cordova, J.C.*, Olivares A.O.*, Shin, Y.*, Stinson, B.M., Calmat, S., Schmitz, K.R., Aubin-Tam, M.E., Baker, T.A., Lang, M.J., Sauer, R.T. (2014). Stochastic but highly coordinated protein unfolding and polypeptide translocation by the ClpXP proteolytic machine. Cell158: 647-658
(* these authors contributed equally)

Sauer, R. T., Yosefson, O., Stinson, B. M., Nager, A. R., Glynn, S. E., Schmitz, K. R., … & Baker, T. A. (2014). ClpX, a Stochastic Protein Unfolding and Translocation Machine. Biophysical Journal. 106(2): 444a.

Stinson, B.M.*, Nager, A.R.*, Glynn, S.E.*, Schmitz, K.R., Baker, T.A., Sauer, R.T. (2013). Nucleotide binding and conformational switching in the hexameric ring of a AAA+ machine. Cell. 153: 628-639
(* these authors contributed equally)

Stinson, B. M., Glynn, S. E., Nager, A. R., Baker, T. A., Sauer, R. T. (2012). Eliminating ATP Binding in Specific ClpX Subunits Yields Functional ATP-Fueled Protein-Unfolding Machines. Biophysical Journal. 102(3): 21a.

Johnson S.A.*, Stinson B.M.*, Go M.S.*, Reminick J.I.*, Carmona L.M.*, Fang X.*, Baumgart T. (2010). Temperature dependent phase behavior and protein partitioning in giant plasma membrane vesicles. Biochim. Biophys. Act. – Biomembranes 1798, 1427-1435.
(* these authors contributed equally)