Joyce Lee

Post-doc (co-mentored with David Pellman)

617-432-2927

Education

2010-2014 B.S. Biochemistry Pennsylvania State University
2014-2020 Ph.D. Biochemistry Johns Hopkins School of Medicine (supervisor: James Berger)
2021-Present Postdoctoral Fellow Harvard Medical School (supervisor: Johannes Walter and David Pellman)

 

Awards and honors

2018 Ruth L. Kirschstein Predoctoral National Research Service Award
2022 HHMI Jane-Coffin Childs Post-Doctoral fellowship

 

Publications
Lee, J.H., Mosher, E.P., Lee, Y.S., Bumpus, N.N., & Berger, J.M. Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites. Cell Chem Biol. S2451-9456(21)00403-7 (2021)

Lee, J.H. & Berger, J.M. Cell Cycle-Dependent Control and Roles of DNA Topoisomerase II. Genes, 10(11), 859-877 (2019).

Le T.T., Gao X, Park S.H., Lee J, Inman J.T., Lee J.H., Killian J.L., Badman R.P., Berger J.M., & Wang M.D.Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity. Cell, 179(3), 619-631 (2019).

Zhao, B., Arnold, A.L., Coronel, M.A., Lee, J.H., Lee, T, Olejniczak, E.T., & Fesik, S.W. Understanding the Species Selectivity of Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors. Biochemistry, 57(32),  4952-4958 (2018).

Lee, J.H., Wendorff, T.J., & Berger, J.M. Resveratrol: A novel type of topoisomerase II inhibitor.The Journal of Biological Chemistry,292(51), 21011–21022 (2017)