Joyce Lee
Education
2010-2014 | B.S. Biochemistry | Pennsylvania State University |
2014-2020 | Ph.D. Biochemistry | Johns Hopkins School of Medicine (supervisor: James Berger) |
2021-Present | Postdoctoral Fellow | Harvard Medical School (supervisor: Johannes Walter and David Pellman) |
Awards and honors
2018 | Ruth L. Kirschstein Predoctoral National Research Service Award |
2022 | HHMI Jane-Coffin Childs Post-Doctoral fellowship |
Publications
Lee, J.H., Mosher, E.P., Lee, Y.S., Bumpus, N.N., & Berger, J.M. Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites. Cell Chem Biol. S2451-9456(21)00403-7 (2021)
Lee, J.H. & Berger, J.M. Cell Cycle-Dependent Control and Roles of DNA Topoisomerase II. Genes, 10(11), 859-877 (2019).
Le T.T., Gao X, Park S.H., Lee J, Inman J.T., Lee J.H., Killian J.L., Badman R.P., Berger J.M., & Wang M.D.Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity. Cell, 179(3), 619-631 (2019).
Zhao, B., Arnold, A.L., Coronel, M.A., Lee, J.H., Lee, T, Olejniczak, E.T., & Fesik, S.W. Understanding the Species Selectivity of Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors. Biochemistry, 57(32), 4952-4958 (2018).
Lee, J.H., Wendorff, T.J., & Berger, J.M. Resveratrol: A novel type of topoisomerase II inhibitor.The Journal of Biological Chemistry,292(51), 21011–21022 (2017)