Publications

Zhou H, Zaher MS, Walter JC, Brown A (2021) Structure of CRL2Lrr1, the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates.Nucleic Acids Res. 49(22):13194-13206

Low, E., Chistol, G., Zaher, M. S., Kochenova, O. V.,  Walter, J. C. (2020). The DNA replication fork suppresses CMG unloading from chromatin before termination. Genes & development. 34(21-22): 1534-1545.

Lancey, C., Tehseen, M., Raducanu, V. S., Rashid, F., Merino, N., Ragan, T. J., Savva, C.G., Zaher, M.S., Shirbini, A., Blanco, F.J., Hamdan, S.M., De Biasio, A. (2020). Structure of the processive human Pol δ holoenzyme. Nat Commun 11: 1109.

Raducanu, V. S., Rashid, F., Zaher, M. S., Li, Y., Merzaban, J. S., Hamdan, S. M. (2020). A direct fluorescent signal transducer embedded in a DNA aptamer paves the way for versatile metal-ion detection. Sensors and Actuators B: Chemical. 304: 127376.

Kim, D., Rashid. F., Cho, Y,. Zaher, M.S., Cho, I.I.H., Hamdan, S.M., Jeong, C., Lee, J.B. (2019). DNA skybridge: 3D structure producing a light sheet for high-throughput single-molecule imagingNucleic Acids Research, 47 (18): e107.

Sobhy, M. A., Bralić, A., Raducanu, V. S., Tehseen, M., Ouyang, Y., Takahashi, M., Rashid, F., Zaher, M. S., Hamdan, S. M. (2019). Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1. J. Vis. Exp. 151: e60045.

Kim, D., Rashid, F., Cho, Y., Zaher, M.S., Cho, I.I.H., Hamdan, S.M., Jeong, C., Lee, J.B. (2019). DNA skybridge: 3D structure producing a light sheet for high-throughput single-molecule imaging. Nucleic Acids Research. pii: gkz625.

Rashid, F.*, Raducanu, V.S.*, Zaher, M.S.*, Tehseen, M., Habuchi, S., Hamdan, S.M. (2019). Initial state of DNA-Dye complex sets the stage for protein induced fluorescence modulation. Nat Commun. 10 (1): 2104.

Sobhy, M.A., Bralić, A., Raducanu, V.S., Takahashi, M., Tehseen, M., Rashid, F., Zaher, M.S.*, Hamdan, S.M. (2019). Resolution of the Holliday junction recombination intermediate by human GEN1 at the single-molecule level. Nucleic Acids Research. 47 (4): 1935-1949.

Zaher, M.S., Rashid, F.*, Song, B*., Joudeh, L.I., Sobhy, M.A., Tehseen, M., Hingorani, M.M., Hamdan, S.M. (2018). Missed cleavage opportunities by FEN1 lead to Okazaki fragment maturation via the long-flap pathway. Nucleic Acids Research. 46 (6): 2956-2974.(* these authors contributed equally)

Rashid, F., Harris, P.D.*, Zaher, M.S.*, Sobhy, M.A., Joudeh, L.I., Yan, C., Piwonski, H., Tsutakawa, S.E., Ivanov, I., Tainer, J.A., Habuchi, S., Hamdan, S.M. (2017). Single-molecule FRET unveils induced-fit mechanism for substrate selectivity in flap endonuclease 1. eLife. 6: e21884.(* these authors contributed equally)

Zaher, M.S., Oke, M., Hamdan, S.M. (2014). Eukaryotic DNA Replicases. In Molecular Life Sciences: An Encyclopedic Reference, Ellis Bell, Judith S. Bond, Judith P. Klinman, Bettie Sue Siler Masters, Wells RD (eds). Berlin, Heidelberg: Springer-Verlag

Oke, M.,Zaher, M.S., Hamdan, S.M. (2014). Division of Labor. In Molecular Life Sciences: An Encyclopedic Reference, Bell E, Bond JS, Klinman JP, Masters BSS, Wells RD (eds). Berlin, Heidelberg: Springer-Verlag.

Oke, M.,Zaher, M.S., Hamdan, S.M. (2014). PCNA Structure and Interactions with Partner Proteins. In Molecular Life Sciences: An Encyclopedic Reference, Bell E, Bond JS, Klinman JP, Masters BSS, Wells RD (eds). Berlin, Heidelberg: Springer-Verlag.

Oke, M.,Zaher, M.S., Hamdan, S.M. (2014). Mechanism of PCNA loading by RFC. In Molecular Life Sciences: An Encyclopedic Reference, Bell E, Bond JS, Klinman JP, Masters BSS, Wells RD (eds). Berlin, Heidelberg: Springer-Verlag.

Ho, Y.S., Adroub, S.A., Aleisa, F., Mahmood, H., Othoum, G., Rashid, F., Zaher, M.S., Ali, S., Bitter, W., Pain, A., Abdallah, A.M. (2012). Complete Genome Sequence of Mycobacterium fortuitum subsp. Fortuitum Type Strain DSM46621. J. Bacteriol. 194 (22): 6337-6338.