Martha Longley
Education
| 2014-2018 | B.S. Biochemistry | Yale University |
| 2020-Present | MD/PhD student Harvard/MIT | Harvard Medical School (supervisor: Johannes Walter) |
Awards and honors
| Magna Cum Laude (Yale University) | |
| Phi Beta Kappa (Yale University) | |
| Pat Wilde Prize (Yale University) | |
| Intramural Research Training Award (NIH) |
Publications
Longley, J. Lee, J. Jung, F.W. Lohoff, Epigenetics of Alcohol Use Disorders – A Review of Recent Advances in Methylation Profiling,Addiction Biology,2021. doi: 10.1111/adb.13006.
F.W. Lohoff, A. Roy, J. Jung, M. Longley, D. Rosoff, A. Luo, E. O’Connell, J. Sorcher, H. Sun, M. Schwandt, C. Hodgkinson, D. Goldman, R. Momenan, A. McIntosh, M. Adams, R. Walker, K. Evans, A. Murray, D. Porteous, A. Smith, J. Lee, C. Muench, K. Charlet, T. Clarke, Z. Kaminsky, Epigenome-wide association study and multi-tissue replication of individuals with alcohol use disorder: evidence for abnormal glucocorticoid signaling pathway gene regulation, Molecular Psychiatry, 2020. doi: 10.1038/s41380-020-0734-4.
Luo*, J. Jung*,M. Longley, D.B. Rosoff, K. Charlet, C. Muench, J. Lee, C. Hodgkinson, Z.A. Kaminsky, F.W. Lohoff, DNA methylation age and GWAS of epigenetic aging rates in AUD reveals a role for APOL2,Neuropsychopharmacology, 2020, 45(2):327-336. doi: 10.1038/s41386-019-0500-y. *equal contribution
Cole, N. Planavsky,M. Longley, P. Boning, D. Wilkes, X. Wang, E. Swanner, C. Wittkop, V. Busigny, A. Knudsen, E. Sperling, Uranium isotope fractionation in anoxic settings and the global uranium isotope mass balance,Global Biogeochemical Cycles, 2020. doi: 10.1029/2020GB006649
D.B. Rosoff*, K. Charlet*, J. Jung, J. Lee, C. Muench, A. Luo, M. Longley, F.W. Lohoff, Lipid profile dysregulation predicts alcohol withdrawal symptom severity in individuals with alcohol use disorder, Alcohol, 2020, S0741-8329(20)30178-6. doi:10.1016/j.alcohoo.2020.02.164 *equal contribution
Jung*, D.B. Rosoff*, C. Muench, A. Luo,M. Longley, J. Lee, K. Charlet, F.W. Lohoff, Adverse childhood experiences are associated with high-intensity binge drinking behavior in adulthood and mediated by psychiatric disorders,Alcohol and Alcoholism, 2020, 55(2):204-214. doi: 10.1093/alcalc/agz098. *equal contribution
D.B. Rosoff, K. Charlet, J. Jung, J. Lee, C. Muench, A. Luo, M. Longley, K.L. Mauro, F.W. Lohoff, Association of high-intensity binge drinking with lipid and liver function enzyme levels, JAMA Network Open, 2019, 20192
Lee, D.B. Rosoff, A. Luo,M. Longley, M. Phillips, K. Charlet, C. Muench, J. Jung, F.W. Lohoff, PCSK9 is increased in cerebrospinal fluid of individuals with alcohol use disorder,Alcoholism: Clinical and Experimental Research, 2019, 43:1163-1169.