Olga Kochenova
2003-2007 | B.S. Biology | Saint Petersburg State University, Russia (supervisor: Elena I. Stepchenkova) |
2007-2009 | M.S. Biology (Genetics) | Saint Petersburg State University, Russia (supervisor: Elena I. Stepchenkova) |
2010-2016 | Ph.D. Oncology and Cancer Biology | University of Nebraska Medical Center (supervisor: Polina V. Shcherbakova) |
2016-Present | Postdoctoral fellow | Harvard Medical School (supervisor, Johannes Walter) |
2013-2015 | UNMC Program of Excellence Graduate Assistantship |
Low E, Chistol G, Zaher MS, Kochenova OV, Walter JC.Genes Dev. 2020 Nov 1;34(21-22):1534-1545. doi: 10.1101/gad.339739.120. Epub 2020 Sep 17.PMID: 32943574
Deng, L., Wu, R.A., Sonneville, R., Kochenova, O.V. , Labib, K., Pellman, D., Walter, J.C (2019). Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements. Mol Cell. 73(5): 915-929.
Wu, R.A., Semlow, D.R., Kamimae-Lanning, A.N., Kochenova, O.V. , Chistol, G., Hodskinson, M.R., Amunugama, R., Sparks, J.L., Wang, M., Deng, L., Mimoso, C.A., Low, E., Patel, K.J., Walter, J.C. (2019). TRAIP is a master regulator of DNA interstrand crosslink repair. Nature. doi:10.1038/s41586-019-1002-0.
Kochenova O.V.*, Bezalel-Buch R.*, Tran P., Chabes A., Burgers P.M.J. and Shcherbakova P.V. (2017). Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations. Nucleic Acid Res. 45(3): 1200-1218.
(* these authors contributed equally)
Kochenova O.V., Daee D.L., Mertz T.M., Shcherbakova P.V. (2015). DNA Polymerase ζ-Dependent Lesion Bypass in Saccharomyces cerevisiae Is Accompanied by Error-Prone Copying of Long Stretches of Adjacent DNA. PLoS Genet. 11(3): e1005110.
Stepchenkova E.I., Kochenova O.V., Zhuk A.S., Andreĭchuk Iu.V., Inge-Vechtomov S.G. (2011). Phenotypic expression and inter-conversion of primary lesions of genetic material detectable in the alpha-test in yeast Saccharomyces cerevisiae. Gig Sanit.: 64-9.
Sharma N.M., Kochenova O.V., Shcherbakova P.V. (2011). The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell nuclear antigen (PCNA) regulates the Rev1-PCNA interaction and Polζ/Rev1-dependent translesion DNA synthesis. J Biol Chem. 286(38): 33557-66.
Kochenova O.V., Soshkina J.V., Stepchenkova E.I., Inge-Vechtomov S.G., Shcherbakova P.V. (2011). Participation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in yeast Saccharomyces cerevisiae. Biochemistry (Moscow). 76(1): 49-60.
Northam M.R., Robinson H.A., Kochenova O.V., Shcherbakova P.V. (2010). Participation of DNA polymerase ζ in replication of undamaged DNA in Saccharomyces cerevisiae. Genetics. 184(1): 27-42.