Ryan Grainger

Post-doc

617-432-2927

Education

2012-2016 B.M.Sc., Microbiology and Biochemistry University of Western Ontario
2016-2022 PhD, Biochemistry University of Western Ontario (supervisor Murray Junop)
2023-Present Post-doc Harvard Medical School (supervisor: Johannes Walter)

Awards and honors

5/2020 Doctoral Postgraduate Scholarship, Natural Sciences and Engineering Research Council of Canada (NSERC)
6/2017 Canadian Graduate Master’s Scholarship, Canadian Institutes of Health Research (CIHR)
9/2016 Ontario Graduate Scholarship

Publications
Balachandran N, Grainger R, Rob T, Liuni P, Wilson D, Junop M, Berti P. (2022) DAHP synthase: half-of-sites reactivity and inter-subunit communications in DAHP synthase catalysis and regulation. ACS Biochemistry 61(20), 2229-2240.

Buzon B*, Grainger R*, Rzadki C, Huang S, Junop M. (2021) Identification of bioactive SNM1A inhibitors. ACS Omega 6(14), 9352-9361.

Heimhalt M, Mukherjee P, Grianger R, Szabla R, Brown C, Turner R, Junop M, Berti P. (2021) An inhibitor-in-pieces approach to DAHP synthase inhibition: potent enzyme and bacterial growth inhibition. ACS Infectious Disease 7(12), 3292-3302.

Buzon B, Grainger R, Huang S, Rzadki C, Junop M. (2018) Structure-specific endonuclease activity of SNM1A enables processing of a DNA interstrand crosslink. Nucleic Acids Res 46(17), 9057-9066.

Hobbies
Camping/Hiking and Reading