Smriti Pandey
| 2015-2019 | B.A. Biochemistry | Mount Holyoke College (supervisor, Katherine E. Berry) |
| 2019-2024 | Ph.D. Biology and Biomedical Sciences | Harvard University (supervisor, David R. Liu) |
| 2018 | Louisa Stone Stevenson Prize for Excellence in Chemistry (Mount Holyoke College) |
| 2019 | Gertrude “Bobby” Lerch Award in Biochemistry (Mount Holyoke College) |
| 2019 | Phi Beta Kappa (Mount Holyoke College) |
| 2024 | Stuart L. Schreiber prize in Scientific Excellence for Graduate Students (Broad Institute) |
| 2024 | Forbes 30 under 30 Healthcare, Class of 2025, North America |
Tao, Y.A.*; Sakai, H.A.*; Jiang, A.Y.*; Krasnow, N.A.*; Vaganov, V.S.; Shim, B.; Barsdale, Z.; Ahmed, N.; Na, M.; Pandey, S.; Cristian, A.; Zhang, E.; Xu, J.A.; Bulcaen, M.; Liu, D.R. “AI-guided re-design of laboratory-evolved reverse transcriptases enhances prime editing in human cells and in animals.” Nature Biotechnology (2026).
Hsu, A.*; Chen, P.J.*; Li, A.H.*; Hemez, C., Gao, X.D.; Terry, M.; Nelson, C.; Selvam, V.; Christian, A.; McElroy, A.; Steinbeck, B.J.; Mahadeshwar, G.K.; Pandey S.; Barsdale, Z.; Chen, P.Z.; Sousa, A.A.; Sakai, H.A.; Silverstein, R.A.; Morad, I.; Krueger, R.K.; Shen, M.W.; Kleinsteiver, B.P.; Lutz, C.M.; Tolar, J.; Blazar, B.R.; Osborn, M.J.; Liu, D.R. “Mechanistic machine learning enables interpretable and generalizable prediction of prime editing.” Nature Biotechnology (2026).
Sousa, A.A.*; Hemez, C.*; Lei, L.; Traore, S.; Kulhankova, K.; Newby, G.A.; Doman, J.L.; Oye, K.; Pandey, S.; Karp, P.H.; McCray, P.B.; Liu, D.R. “Systematic optimization of prime editing for the efficient functional correction of CFTR F508del in human airway epithelial cells” Nature Biomedical Engineering (2024).
Pandey S.*; Gao, X.D.*; Krasnow, N.; McElroy, A.; Tao, Y.A.; Duby, J.E.; Steinbeck, B.J.; McCreary, J.; Pierce, S.E.; Tolar, J.; Meissner, T.B.; Chaikof, E.L.; Osborn, M.J.; Liu, D.R. “Efficient and versatile programmable large-gene integration in mammalian cells enabled by continuously evolved recombinases and prime editing” Nature Biomedical Engineering (2024).
Steinbeck, B.J.*; Gao, X.D.*; McElroy, A.N.; Pandey, S.; Doman, J.L.; Riddle, M.J.; Xia, L.; Chen, W.; Eide, C.R.; Lengert, A.H.; Han, S.W.; Blazar, B.R.; Wandall, H.H.; Dabelsteen, S.; Liu, D.R.; Tolar, J.; Osborn, M.J. “Twin prime editing mediated exon skipping/reinsertion for restored collagen VII expression in recessive dystrophic epidermolysis bullosa” Journal of Investigative Dermatology (2024).
Doman, J.L.*; Pandey, S.*; Neugebauer, M.E.; An, M.; Davis, J.R.; Randolph, P.B.; McElroy, A.; Gao, X.D.; Raguram, A.; Richter, M.F.; Everette, K.E.; Banskota, S.; Tian, K.; Tao, Y.A.; Tolar, J.; Osborn, M.J.; Liu, D.R. “Phage-assisted evolution and protein engineering yield compact, efficient prime editors” Cell 186, 3983-4002 e3926 (2023).
Neugebauer, M. E.; Hsu, A., Arbab, M.; Krasnow, N. A.; Pandey, S.; Doman, J. L.; McElroy, A. N.; Huang, T. P.; Raguram, A.; Banskota, S.; Newby, G. A.; Tolar, J.; Osborn, M. J.; Liu, D. R. “Evolution of an Adenine Base Editor into a Small, Efficient Cytosine Base Editor with Low Off-Target Activity” Nature Biotechnology41, 673–685 (2023).
Pandey, S.; Gravel, G.M.; Stockert, O.M.; Wang, C.D.; Hegner, C.L.; LeBlanc, H., Berry, K.E. “Genetic identification of the functional surface for RNA binding by Escherichia coli ProQ” Nucleic Acids Research 48, 8, 4507-4520 (2020).
Hobbies
Cooking, walking, watching TV